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药物控释高分子材料要求有良好的生物相容性．经对聚天冬酰胺系列材料进行皮下埋植实验、组织病理学观察、血生化和微核等检测得知，在埋植部位早期出现异物反应，第１３天部分小鼠肝组织小血管边出现少量炎性细胞，３４天后上述细胞逐渐减少或消失，肝肾组织细胞的形态和功能基本正常，埋植部位皮肤切口愈合良好．实验表明，聚天冬酰胺材料具有良好的生物相容性
Drug controlled release polymer materials require good biocompatibility. Subcutaneous implants, histopathological observation, blood biochemistry and micronucleus test of polyaspartamide series materials revealed that there was early foreign body reaction at the site of implantation. On the 13th day, some small blood vessels in the liver tissue appeared A small amount of inflammatory cells, 34 days after the above-mentioned cells gradually reduced or disappeared, liver and kidney cells morphology and function was normal, the implant site skin incision healed well. Experiments show that polyaspartamide material has good biocompatibility