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目的观察米索前列醇防治孕妇产后大出血的临床效果。方法选择收治的74例有产后大出血高危因素产妇为研究对象,随机分为对照组和观察组。对照组给予静脉滴注缩宫素预防性治疗,观察组给予米索前列醇舌下含服预防性治疗。比较两组治疗后产后大出血发生率及出后2 h、24 h出血量。结果观察组产后大出血发生率显著低于对照组,差异有统计学意义(P<0.01)。观察组产后2 h出血量、产后24 h出血量显著少于对照组,差异有统计学意义(P<0.05)。观察组血红蛋白、红细胞比容下降幅度显著低于对照组,差异有统计学意义(P<0.05)。结论米索前列醇防治孕妇产后大出血疗效确切,可显著减少出血发生率及出血量。
Objective To observe the clinical effect of misoprostol in preventing and treating postpartum hemorrhage in pregnant women. Methods Choose 74 cases of maternal high risk factors for postpartum hemorrhage as research object, were randomly divided into control group and observation group. Control group was given intravenous oxytocin prophylactic treatment, the observation group was given misoprostol sublingual administration of prophylactic treatment. The incidence of postpartum hemorrhage and the amount of hemorrhage after 2 h and 24 h were compared between the two groups. Results The incidence of postpartum hemorrhage in observation group was significantly lower than that in control group (P <0.01). The amount of bleeding in observation group 2 h postpartum was significantly lower than that in control group 24 h postpartum, the difference was statistically significant (P <0.05). The decrease of hemoglobin and hematocrit in the observation group was significantly lower than that in the control group (P <0.05). Conclusion Misoprostol in the prevention and treatment of postpartum hemorrhage in pregnant women is effective, can significantly reduce the incidence of bleeding and bleeding.