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细胞表面糖蛋白是细胞膜的主要成份之一,肿瘤细胞膜糖蛋白的改变,可能是癌细胞出现生物学功能变化的基础。糖蛋白抗原的研究已成为肿瘤基础理论和诊断治疗研究中的一个重要方面。目前肝癌糖蛋白类研究的结果表明,肝癌细胞的岩藻糖化改变很有特征性,提示肝癌细胞的异常岩藻糖化在肝癌的发生和细胞异常生物学活动中具有相当重要的意义。
Cell surface glycoprotein is one of the main components of cell membrane. The change of tumor cell membrane glycoprotein may be the basis of biological function changes in cancer cells. The study of glycoprotein antigens has become an important aspect of tumor basic theory and diagnostic therapy research. At present, the results of studies on glycoproteins in hepatocellular carcinoma indicate that the fucosylation of hepatoma cells is very characteristic, suggesting that the abnormal fucosylation of hepatoma cells is of great significance in the development of hepatocellular carcinoma and abnormal biological activities of cells.