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多酶片主要含有胃蛋白酶、淀粉酶和胰酶,是胃肠道中主要酶的混合物,它们能促进碳水化合物、蛋白质的消化。对消化不良、食欲不振有一定疗效。本刊1979年第9期422页曾有报道,认为多酶片由于胃蛋白酶、淀粉酶和胰酶混合包在片内,处方不合理。对此,特提出以下看法,供参考。在上海、湖南、广东等地方药品标准中均写明本品为双层片。它的基本生产工艺为:胰酶、淀粉酶与其它制粒、压片、包肠溶衣;在肠衣外包胃蛋白酶和包糖衣……。本品经过人体胃液时,胃蛋白酶在酸性环境中发挥其消化作用;其它酶在肠溶衣的保护下,顺利通过胃液,到达肠内,在碱性环境中发挥消化作用。因此它们之间的干扰是非常少的,认为三种酶配伍在一起不能发挥作用的说法是欠妥的。
Multi-enzyme tablets mainly contain pepsin, amylase and pancreatin, is a mixture of major enzymes in the gastrointestinal tract, they can promote the digestion of carbohydrates, proteins. On indigestion, loss of appetite have a certain effect. Articles No. 9, 1979, 422 pages have been reported, that multi-enzyme tablets due to pepsin, amylase and pancreatin enzyme package wrapped in tablets, the prescription is not reasonable. In this regard, special mention the following views for reference. In Shanghai, Hunan, Guangdong and other local drug standards are made clear that the product is double-layer film. Its basic production process is: trypsin, amylase and other granulation, tabletting, enteric coated; in the enteric coated pepsin and sugar-coated ....... This product through the human gastric juice, pepsin in the acidic environment to play its digestive function; other enzymes in the enteric coating under the protection of smooth through the gastric juice, reach the intestine, in the alkaline environment to play a digestive role. So the interference between them is very small, that the three enzymes can not play a role in the combination of claims is not appropriate.