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目的分析肾移植术后影响其生存率的原因,以期提高其肾移植存活率及效果。方法回顾性分析2001年1月到2011年7月间于我院施行肾移植手术的患者220例,对肾移植术后随访患者的生存时间及死亡原因进行统计学分析。结果 220例肾移植病例随访期间10年内死亡的病例共27例,死亡率约为12.3%,其中12例(44.4%)死于肾移植术后感染,8例(29.6%)死于肾移植术后心、脑血管疾病,3例(11.1%)死于肝功能衰竭,1例(3.7%)死于肾移植后移植肾破裂出血,2例(7.4%)死于移植后恶性肿瘤,1例(3.7%)因经济原因放弃治疗。结论感染仍然是当前影响肾移植术后患者生存率的第一位因素;心脑血管疾病已成为中老年肾移植患者术后生存的重要因素。
Objective To analyze the reasons that influence the survival rate after renal transplantation in order to improve the survival rate and effect of renal transplantation. Methods A retrospective analysis of 220 patients who underwent renal transplantation in our hospital from January 2001 to July 2011 was performed. The survival time and cause of death after the renal transplantation were analyzed statistically. Results A total of 27 deaths occurred in 220 cases of renal transplantation within 10 years of follow-up, with a mortality rate of 12.3%. Of these, 12 (44.4%) died of renal transplant infection and 8 (29.6%) died of renal transplantation 3 cases (11.1%) died of liver failure, 1 case (3.7%) died of renal allograft rupture after transplantation, 2 cases (7.4%) died of malignant tumor after transplantation, and 1 case (3.7%) gave up treatment for economic reasons. Conclusions Infection is still the first factor affecting the survival rate of patients after renal transplantation. Cardiovascular disease has become an important factor for postoperative survival in middle-aged and elderly renal transplant recipients.