虽然传统上功能磁共振成像(fMRI)评价肌骨系统肿瘤的作用是在治疗前帮助确定病变的侵犯范围,但是其作用随着新技术出现发生了变化。近期Johns Hopkins医学院的学者通过多参数MR评价肌骨肉瘤,其研究重点是脉冲序列在诊断、评估治疗前病变范围、评价肿瘤复发和疗效等方面的作用和潜在价值。作者探讨了解剖、功能性和代谢性MR成像方案,包括化学位移MRI(同相位和反相位)、扩散加权成像(DWI)、灌注成像和MR波谱,T_1WI和液体敏感 Although functional magnetic resonance imaging (fMRI) has traditionally been used to assess the role of musculoskeletal tumors in helping to determine the extent of lesion involvement prior to treatment, its effect has changed as new technologies emerge. Recently, scholars at Johns Hopkins Medical School evaluated musculosarcoma by multi-parametric MR. Its research focuses on the role and potential value of pulse sequence in diagnosis, assessment of the extent of pre-treatment lesion, and evaluation of tumor recurrence and efficacy. The authors explored anatomic, functional, and metabolic MR imaging programs including chemical shift MRI (in-phase and antiphase), diffusion weighted imaging (DWI), perfusion imaging and MR spectroscopy, T_1WI and liquid sensitivity