１　引　言干燥综合征（ＳＳ）是一种侵犯外分泌腺尤以唾液腺和泪腺为主的慢性全身性自身免疫性疾病。干燥综合征在西方国家被认为是仅次于类风湿关节炎的第二种最常见的风湿性疾病［１］。北京郊区普查，原发性干燥综合征的患病率为０．２９％～０．７７％［２］。说明本病并 1 Introduction Sjogren’s syndrome (SS) is a chronic systemic autoimmune disease that attacks exocrine glands especially salivary glands and lacrimal glands. Sjogren’s syndrome is considered as the second most common rheumatic disease in the West after rheumatoid arthritis [1]. Beijing suburbs census, the prevalence of Sjogren’s syndrome is 0.29% ~ 0.77% [2]. Explain the disease and