目的:评价盐酸布桂嗪在设定的色谱条件下能否有效地检出残留的苯溶剂。方法:精密量取苯储备液适量,加二甲基甲酰胺:水(51)溶液溶解并稀释成0.000 2mg/mL的溶液作为对照品溶液,对检测方法的精密度、准确度、线性和检测限进行实验。结果:在设定的色谱条件下能够有效地检出盐酸布桂嗪残留的苯。结论:此方法可以用于盐酸布桂嗪原料药中苯残留的检测。 OBJECTIVE: To evaluate whether the residual benzol solvent can be detected effectively by Buzine hydrochloride under the chromatographic conditions. Methods: The precise amount of benzene stock solution appropriate, plus dimethyl formamide: water (5  1) solution was dissolved and diluted to 0.000 2mg / mL solution as the reference solution, the detection accuracy, accuracy, linearity And detection limit experiment. Results: Under the set chromatographic conditions, the benzene residues in buzine hydrochloride can be detected effectively. Conclusion: This method can be used for the determination of benzene residues in the active substance of buzine hydrochloride.