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目的探讨我院分娩的出生缺陷儿临床类型与产前超声诊断分析,为孕期早期诊断出生缺陷提供科学依据。方法回顾性分析我院2001年至2009年共分娩28 311例,出生缺陷儿426例,发生率15‰,产前超声诊断269例,(检出率63.1%),我院采取产科超声检查三个重点时间段进行筛查(孕龄10-14周,22-26周及32-36周)检测胎儿发育情况。结果孕龄14-27周超声检查出生缺陷人工终止妊娠92例(21.59%),出生缺陷发生率前五位依次为:神经管畸形(21.8%),唇腭裂(16.9%),多指并指(趾)畸形(10.01%),胎儿水肿(9.85%),外耳畸形(4.22%),产前超声检出率分别为:95.69%,50.72%,9.30%,80.95%,0,结论产前超声诊断除神经管畸形,胎儿水肿,唇腭裂外,其它发病率较高的畸形超声检出率较底,因此加强产前诊断人员的技术培训,提高超声诊断技术水平,是提高人口素质降低出生缺陷的重要措施。
Objective To investigate the clinical types and prenatal diagnosis of birth defects in our hospital and to provide a scientific basis for early diagnosis of birth defects during pregnancy. Methods A retrospective analysis of our hospital from 2001 to 2009 28 311 cases of childbirth, birth defects in 426 cases, the incidence of 15 ‰, 269 cases of prenatal diagnosis of ultrasound (detection rate was 63.1%), our hospital to take obstetric ultrasound three A key period of screening (gestational age 10-14 weeks, 22-26 weeks and 32-36 weeks) to detect fetal development. Results The gestational age of 14-27 weeks ultrasound examination of birth defects in 92 cases of artificial termination of pregnancy (21.59%), the incidence of birth defects in the top five were: neural tube defects (21.8%), cleft lip and palate (16.9%), (10.01%), fetus edema (9.85%) and deformity of the outer ear (4.22%). The rates of prenatal ultrasound were 95.69%, 50.72%, 9.30% and 80.95%, respectively. Conclusions Prenatal ultrasound In addition to the diagnosis of neural tube defects, fetal edema, cleft lip and palate, the incidence of other higher incidence of abnormal ultrasound ultrasound at the end, so strengthening prenatal diagnostic staff training to improve the level of ultrasound diagnosis is to improve the quality of the population to reduce birth defects Important measure.