论文部分内容阅读
端粒酶是维持细胞端粒长度的逆转录酶，由模板ＲＮＡ及催化蛋白亚基组成，其活性被认为与癌细胞永生化有关。ｈＴＲ是由Ｓｉｎｇｅｒ等人从ＨＥＬＡ细胞中分离克隆出的人类端粒酶ＲＮＡ模板基因。研究已证实在干细胞及肿瘤细胞中ｈＴＲ比正常细胞高表达。为了探讨胃癌的发...
Telomerase is a reverse transcriptase that maintains the telomere length of a cell. It consists of a template RNA and a catalytic protein subunit, and its activity is thought to be related to the immortalization of cancer cells. hTR is a human telomerase RNA template gene isolated and cloned from HELA cells by Singer et al. Studies have confirmed that hTR is expressed higher than normal cells in stem cells and tumor cells. In order to discuss the development of gastric cancer...