自噬是胞浆大分子物质和细胞器在膜包囊泡中降解的生物学过程,具有多种生理功能。在某些情况下,自噬可以导致细胞死亡,即自噬性细胞死亡。近年研究表明,自噬和恶性肿瘤发生、发展有密切关系。靶向自噬途径有可能成为治疗肿瘤的新方法。 Autophagy is a biological process of degradation of cytoplasmic macromolecules and organelles in membrane vesicles, and has various physiological functions. In some cases, autophagy can lead to cell death, the death of autophagic cells. In recent years, studies have shown that the occurrence of autophagy and malignant tumors, the development is closely related. Targeting autophagy may be a new way to treat tumors.