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目的探讨毛母质瘤的临床及病理特征,以提高临床与病理诊断符合率。方法对术前误诊为皮脂腺囊肿、钙化性粉瘤、慢性淋巴结炎,表皮样囊肿,纤维瘤,脂肪瘤等31例病例的临床及病理学特点进行回顾性分析。结果术后大体所见:大部分肿瘤有完整的包膜,壁薄,质地较硬,切面呈灰白色,表面有钙化,有“沙粒”、“豆腐渣样”或“石灰样”颗粒;镜下所见:肿瘤细胞呈不规则团块状,外周的细胞类似基底细胞,核深嗜碱性,向中央细胞核逐渐浓缩消失成为影细胞。影细胞境界清楚、弱嗜碱性,细胞中央有一不着色消失的核影子。部分细胞巢中央间钙化,间质内可见巨细胞反应。病理组织学证实为毛母质瘤。结论进一步增强对毛母质瘤临床及病理特征的认识,以利于提高诊断准确率。
Objective To investigate the clinical and pathological features of hairy tumor and improve the coincidence rate of clinical and pathological diagnosis. Methods The clinical and pathological features of 31 cases misdiagnosed as sebaceous gland cyst, calcific amyloidoma, chronic lymphadenitis, epidermoid cyst, fibroma and lipoma were retrospectively analyzed. Results The results showed that most of the tumors had intact capsule, thin wall, hard texture, gray and white section and calcified surface with “sand”, “tofu-like” or “lime” Microscopically, the tumor cells showed irregular lumps. The peripheral cells were similar to the basal cells, and the nucleus was deep basophilic and gradually disappeared into the shadow cells in the central nucleus. Shadow cell state clear, weakly basophilic, the central cell has a non-color disappear nuclear shadow. Part of the central cell calcification, interstitial visible giant cell response. Histopathology confirmed as hairy tumor. Conclusion To further enhance the understanding of the clinical and pathological features of the tumors, in order to improve the diagnostic accuracy.