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大量临床资料表明,抗痨药物可引起肝功能损害,本文通过100例肺结核住院患者的分组化疗观察,进一步讨论抗痨药物的肝损情况及防治措施。临床资料一、一般资料:男性70人,女性30人。20～40岁45人,41～60岁35人,61岁以上20人。肺结核分型:Ⅲ型96例,空洞型15例,伴渗出性胸膜炎5例,Ⅱ型肺结核1例,Ⅳ型肺结核3例。全部病人都连续痰涂片查结核菌三次,以后每月复查一次。痰菌涂阳者55例,痰涂片阴性者45例。服药前均进行肝功能检查,肝功能异常者,加做两对半检查及肝、胆B超探查。治疗方案:分为利福平组(2SHRE/7HR)
A large number of clinical data show that anti-tuberculosis drugs can cause liver damage. In this paper, 100 cases of tuberculosis inpatient chemotherapy in the group to further discuss the anti-tuberculosis drugs liver damage and prevention and treatment measures. Clinical data First, the general information: 70 men and 30 women. 20-40 years old 45 people, 41-60 years old 35 people, 61 people over 20 years old. Tuberculosis type: 96 cases of type Ⅲ, empty type in 15 cases, with exudative pleurisy in 5 cases, type Ⅱ tuberculosis in 1 case, type Ⅳ tuberculosis in 3 cases. All patients were sputum smear check TB three times, after a monthly review. Sputum smear positive 55 cases, sputum smear negative in 45 cases. Before taking medication liver function tests, abnormal liver function, plus two and a half checks and liver and gallbladders B-probe. Treatment options: divided into rifampicin group (2SHRE / 7HR)