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目的探讨新生儿术后发生手术部位感染的相关因素,为制定预防控制措施提供依据。方法对2012年6月-2016年5月新生儿病区所有手术患儿进行前瞻性队列研究,对手术部位感染的相关因素进行多因素Logistic回归分析。结果 2 366例新生儿发生手术部位感染62例,感染率为2.62%;多因素Logistic回归分析结果显示10 min Apgar评分8~10分(OR=0.237,95%CI:0.084~0.668)是新生儿手术部位感染的保护因素,早产儿(OR=2.912,95%CI:1.103~5.435)、ASA评分超过Ⅲ级(OR=1.992,95%CI:1.174~3.379)、手术持续时间超过180 min(OR=2.837,95%CI:1.540~5.228)及留置引流管(OR=2.573,95%CI:1.401~4.724)是新生儿手术部位感染的危险因素。结论应针对上述危险因素采取相应的干预措施,加强高危患儿的围手术期的管理,降低新生儿术后手术部位感染的发生率。
Objective To investigate the related factors of postoperative infection of surgical site in neonates and provide basis for prevention and control measures. Methods A prospective cohort study was conducted in all neonates with neonatal ward from June 2012 to May 2016. Multivariate Logistic regression analysis was performed on the related factors of surgical site infection. Results In 626 neonates, 62 cases were infected with the surgical site, the infection rate was 2.62%. Logistic regression analysis showed that the Apgar score was 10 to 10 points (OR = 0.237, 95% CI: 0.084-0.668) The protective factors of surgical site infection were premature infants (OR = 2.912, 95% CI: 1.103-5.435), ASA score more than grade III (OR = 1.992, 95% CI: 1.174-3.379) = 2.837, 95% CI: 1.540 ~ 5.228) and indwelling drainage tube (OR = 2.573, 95% CI: 1.401 ~ 4.724) were the risk factors of infection in the surgical site of neonates. Conclusions Corresponding intervention measures should be taken according to the above risk factors to improve perioperative management of high-risk children and reduce the incidence of postoperative surgical site infection in neonates.