论文部分内容阅读
目的观察益气养阴方联合TP方案治疗非小细胞肺癌(NSCLC)的近期疗效和毒副反应。方法将62例NSCLC患者随机分为治疗组(32例)和对照组(30例),均采用TP方案化疗2个周期。治疗组在化疗的基础上给予益气养阴方治疗,观察两组近期疗效、生活质量、中医证候、体重变化以及毒副反应。结果治疗后试验组患者在近期疗效、生活质量、中医证候疗效和体重变化、不良反应发生率等方面均优于对照组,差异均有统计学意义(P<0.05)。结论益气养阴方联合TP方案治疗晚期气阴两虚型NSCLC,可提高临床疗效,改善生活质量,减轻化疗毒副反应,延长生存期。
Objective To observe the short-term curative effect and toxicity of Yiqi Yangyin prescription combined TP regimen in the treatment of non-small cell lung cancer (NSCLC). Methods Sixty-two patients with NSCLC were randomly divided into treatment group (n = 32) and control group (n = 30). All patients were treated with TP regimen for 2 cycles. On the basis of chemotherapy, the treatment group was given Yiqi Yangyin Prescription, and the two groups were observed the short-term curative effect, quality of life, TCM syndromes, body weight changes and toxic and side effects. Results After treatment, the patients in the experimental group were better than the control group in terms of short-term efficacy, quality of life, curative effect of TCM syndromes and body weight, and the incidence of adverse reactions. The differences were statistically significant (P <0.05). Conclusions The combination of Yiqi Yangyin prescription and TP regimen in the treatment of advanced qi and yin-deficiency syndrome type NSCLC can improve clinical curative effect, improve quality of life, reduce chemotherapy side effects and prolong survival.