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从298例肺癌患者资料中,收集到有脑部转移者26例,分析临床首发症状、脑间转移灶数目、病理类型,及治疗方式四个因素与生存期的关系。结果表明,肺鳞癌及腺癌脑转移的生存期较之小细胞肺癌脑转移长。采取综合治疗(肺内或脑转移灶切除,配合术后放疗及化疗)比单一非手术治疗生存期长。颅内脑转移灶数目对生存期的影响在本组资料中单发脑转移、多发脑转移生存期在两组间无明显差异。而首发症是以肺内为首发,或与脑部症状为首发生存期在二者间也无显著性差异。从而说明,肺癌本身预后很差,给予原发灶手术切除及转移灶切除或放疗可望延长生存期及生存质量。
From 298 cases of lung cancer, we collected 26 cases of brain metastases, and analyzed the relationship between the first symptom, the number of metastatic brain lesions, the pathological types, and the treatment methods and the survival time. The results showed that lung squamous cell carcinoma and adenocarcinoma of brain metastasis than the survival of small cell lung cancer brain metastasis longer. To take comprehensive treatment (lung or brain metastases resection, with postoperative radiotherapy and chemotherapy) than a single non-surgical treatment of long survival. The impact of the number of intracranial brain metastases on the survival of single brain metastases in this group of data, multiple brain metastasis of survival in the two groups no significant difference. The first symptom is based on the lung as the first episode, or with the onset of brain symptoms in the two no significant difference between the two. Thus, the poor prognosis of lung cancer itself, given the surgical resection of the primary tumor and metastases resection or radiotherapy is expected to extend the survival and quality of life.