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90患者分为MS合并T2DM组、肥胖合并T2DM组、单纯肥胖组,健康对照组各30例。结果肥胖各组血清抵抗素、胰岛素抵抗指数(HOMA-IR)均高于对照组(P<0.01),血清脂联素水平均低于对照组(P<0.01)。多元线性逐步回归分析显示,体质量指数(BMI)、FPG、脂联素、抵抗素是影响老年MS患者IR的独立危险因素。结论老年MS患者在疾病各个时期均存在IR,脂联素、抵抗素可影响老年MS患者IR的程度。
90 patients were divided into MS with T2DM group, obese with T2DM group, simple obesity group and healthy control group with 30 cases each. Results The levels of serum resistin and insulin resistance index (HOMA-IR) in obesity group were significantly higher than those in control group (P <0.01). Serum levels of adiponectin were lower than those in control group (P <0.01). Multivariate linear stepwise regression analysis showed that body mass index (BMI), FPG, adiponectin and resistin were independent risk factors influencing IR in elderly MS patients. Conclusion Elderly MS patients have IR, adiponectin and resistin in different stages of the disease, which may affect the IR of elderly MS patients.