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目的比较氟康唑与酮康唑口服治疗复发性念珠菌阴道炎的临床疗效。方法 180例复发性念珠菌阴道炎患者,分成酮康哇组和氟康哇组。氟康哇组采用氟康哇治疗,酮康哇组采用酮康哇治疗。结果氟康哇组总有效率97.78%与酮康哇组94.44%相比,差异无统计学意义(P>0.05)。氟康哇组不良反应病例发生率3.33%少于酮康哇组11.11%,差异有统计学意义(P<0.05)。结论氟康唑与酮康唑治疗复发性念珠菌阴道炎均疗效可靠,但氟康唑组不良反应发生率少。
Objective To compare the clinical efficacy of oral administration of fluconazole and ketoconazole in the treatment of recurrent Candida vaginitis. Methods 180 cases of recurrent Candida vaginitis patients, divided into ketocona group and fluconazole group. Fluconazole group with fluconazole treatment, ketocona group with ketoconazole treatment. Results The total effective rate in fluconazole group was 97.78% compared with that in ketoconazole group 94.44%, there was no significant difference (P> 0.05). The incidence of adverse reactions in fluconazole group was 3.33% less than that in ketocona group (11.11%), the difference was statistically significant (P <0.05). Conclusion Both fluconazole and ketoconazole are effective in the treatment of recurrent Candida vaginitis, but there is little adverse reaction in the fluconazole group.