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采用放射免疫法（ＲＩＡ） 和Ｖｉｓｕａｌｉｎｅ－ Ⅱ尿液检测盒（ＶＩＩ） 法，分析检测百色地区海洛因依赖者尿液吗啡含量。结果表明：男女组海洛因依赖者尿吗啡含量分别为８１５ ．３６ ±２１６ ．１５ｎｇ／ｍｌ 和５１２ ．１５ ±２１１ ．２６ｎｇ／ｍｌ；ＶＩＩ法均呈阳性反应，符合率为１００ ％ 。正常对照组男女尿吗啡含量分别为２６ ．８１ ±１１ ．２８ｎｇ／ｍｌ 和３１ ．５２ ±１２ ．３６ｎｇ／ｍｌ，接近国内确定的临界值（ ＜ ３０ｎｇ／ｍｌ） ；ＶＩＩ法均呈阴性反应。证实海洛因依赖者尿吗啡含量显著高于正常组（ Ｐ＜ ０ ．０１） ，ＲＩＡ 法和ＶＩＩ法适用于监测人群中海洛因类药物滥用者。尿吗啡动态观察，用保康戒毒冲剂治疗３ ～７ 天后，海洛因依赖者尿吗啡含量趋于正常，提示与该药在体内促进毒物代谢和排泄的作用有一定关系
Radioimmunoassay (RIA) and Visualine- Ⅱ urine test kit (VII) were used to analyze urine morphine content of heroin addicts in Baise area. The results showed that: male and female heroin addicts morphine content were 815. 36 ± 216. 15 ng / ml and 512. 15 ± 211. 26ng / ml; VII method were positive, the coincidence rate was 100%. Urine morphine content of the normal control group were 26. 81 ± 11. 28 ng / ml and 31. 52 ± 12. 36ng / ml, close to the domestic critical value (<30ng / ml); VII method were negative. Confirmed that the content of urine morphine in heroin addicts was significantly higher than that in the normal group (P <0.01). The RIA and VII were suitable for monitoring heroin addicts in heroin addicts. Dynamic observation of urinary morphine, with Baokang drug granules after treatment for 3 to 7 days, urine morphine content of heroin addicts tends to normal, suggesting that the drug in vivo to promote the role of toxic metabolites and excretion have a certain relationship