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目的:探讨性激素替代疗法在更年期妇女保健中的临床应用效果。方法:以2012年6月~2013年6月通城县人民医院收治的148例更年期妇女为研究对象,将其随机分为两组,对照组(74例)予以常规保健治疗,观察组(74例)在常规保健治疗基础上予以性激素替代治疗,观察并比较两组的临床效果。结果:观察组治疗后雌二醇水平明显上升,黄体生成素及卵泡刺激素水平明显下降,差异均有统计学意义(P<0.05),对照组的上述3项指标治疗前后变化不显著,差异无统计学意义(P>0.05);观察组治疗后Kupperman评分改善效果明显好于对照组,差异有统计学意义(P<0.05);观察组治疗后的SCL-90评分明显低于对照组,差异有统计学意义(P<0.05)。结论:性激素替代疗法平衡了更年期妇女的激素水平,相关症状改善显著,值得临床推广应用。
Objective: To investigate the clinical effect of sex hormone replacement therapy in menopausal women’s health care. Methods: A total of 148 cases of climacteric women admitted to Tongcheng County People’s Hospital from June 2012 to June 2013 were randomly divided into two groups. The control group (74 cases) received routine health care. The observation group (74 For example) on the basis of conventional health care to be treated with sex hormone replacement therapy, to observe and compare the clinical effect of the two groups. Results: The estradiol level in the observation group increased significantly, the levels of luteinizing hormone and follicle-stimulating hormone decreased significantly (P <0.05), while those in the control group did not change significantly before and after treatment (P> 0.05). The improvement effect of Kupperman score in the observation group was significantly better than that in the control group (P <0.05). The score of SCL-90 in the observation group was significantly lower than that in the control group The difference was statistically significant (P <0.05). Conclusion: Hormone replacement therapy balance hormone levels in menopausal women, the relevant symptoms improved significantly, worthy of clinical application.