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脑环境的变异可导致血脑屏障(BBB)损害,例如血压的急骤升高、严重的低氧血症或严重的高CO_2血症都可引起 BBB 的损害。作者在以往实验猴中观察到,在室颤数分钟复苏后,有短暂的血压升高、脑血流增多和颅内压升高的现象。通常在10分钟之内,血压回到控制水平,但颅内压下降经常延迟。所以如此,一般认为是脑血管扩张,脑细胞缺氧、水肿和水从血管间隙外渗到血管外所致。是否 BBB 遭受损害,而有血浆成份(白
Variation in the brain environment can lead to damage to the blood-brain barrier (BBB), such as a sudden increase in blood pressure, severe hypoxemia or severe hyper-CO 2 hyperlipidemia that can cause BBB damage. The authors observed in previous experimental monkeys that transient shortening of blood pressure, increased cerebral blood flow, and increased intracranial pressure were observed after a few minutes of ventricular fibrillation. Usually within 10 minutes, blood pressure returns to control level, but the decline in intracranial pressure is often delayed. So, generally considered to be cerebral vasodilation, brain cell hypoxia, edema and water from the extravascular space outside the vascular invasion. Does BBB suffer damage while having plasma components (white