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1成肌细胞分化肌肉发生主要是指在胚胎发育的过程中,其中涉及诸多的生物学过程。在时间上,这一过程可以大致分为以下三个阶段:定向分化、细胞增殖和终极分化[1]。2成肌细胞分化过程中细胞周期的调节成肌细胞分化形成肌管的过程中,成肌细胞从细胞周期中退出,相互融合形成多核的肌管细胞。因此,细胞周期在肌肉发生中起着相当重要
1 Myoblast differentiation Muscle development mainly refers to the process of embryonic development, which involves many biological processes. In time, this process can be broadly divided into the following three stages: directed differentiation, cell proliferation and ultimate differentiation [1]. 2 regulation of cell cycle during myogenic differentiation myoblasts differentiate into myotubes, myoblasts exit from the cell cycle and fuse with each other to form multi-nuclear myotubes. Therefore, the cell cycle plays a very important role in muscle development