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目的探讨甲泼尼龙琥珀酸钠治疗慢性阻塞性支气管炎的临床疗效。方法选取2013年9月—2014年9月于北京市仁和医院接受治疗的慢性阻塞性支气管炎患者70例作为研究对象,将患者分为对照组和观察组,各35例。对照组给予常规激素地塞米松注射液治疗,观察组给予甲泼尼龙琥珀酸钠治疗,比较两组临床疗效、临床症状消失时间、住院时间及不良反应发生情况。结果观察组总有效率高于对照组,肺部啰音消失时间、憋喘消失时间以及住院时间短于对照组,不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论甲泼尼龙琥珀酸钠治疗慢性阻塞性支气管炎的临床疗效显著,可有效减少患者不良反应,安全可靠。
Objective To investigate the clinical efficacy of methylprednisolone sodium succinate in the treatment of chronic obstructive bronchitis. Methods Seventy patients with chronic obstructive bronchitis who were treated in Renhe Hospital of Beijing from September 2013 to September 2014 were selected as the research object, and the patients were divided into control group and observation group, 35 cases each. The control group was given conventional hormone dexamethasone injection. The observation group was treated with methylprednisolone sodium succinate. The clinical efficacy, disappearance of clinical symptoms, hospitalization time and adverse reactions were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group. The time of pulmonary rales disappearing, the time of disappearing of asthma and hospitalization were shorter than that of the control group, and the incidence of adverse reactions was lower than that of the control group. The difference was statistically significant (P <0.05). Conclusion The clinical efficacy of methylprednisolone sodium succinate in the treatment of chronic obstructive bronchitis is significant, which can effectively reduce adverse reactions in patients and is safe and reliable.