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所谓血管炎是指由炎症引起血管破坏的状态。全身性血管炎是1866年由Kussmaul与Maier以结节性动脉周围炎(PAN)首先报告的,至1930年以前,一般认为血管炎都是PAN。呼吸系血管炎与古典PAN有显著区别,即呼吸系血管炎不一定均有肉芽肿,亦无PAN那样症状。PAN的血管炎病变见于细肌性动脉至中等肌性动脉;丽呼吸系血管炎则细动脉与细静脉均有改变。在病理上,呼吸系血管炎分Wegener肉芽肿(WG)、Churg—Strauss症侯群(C—S)和多形性网状细胞病(PMR)/淋巴瘤样肉芽肿(LG)三型,这对临床医生鉴别、诊断及准确地估计预后与决定治疗方法是有益的。
Vasculitis is a state of vasoconstriction caused by inflammation. Systemic vasculitis was first reported by Kussmaul and Maier in 1966 as peripheral nodular periarteritis (PAN). Until 1930, it was generally accepted that vasculitis was PAN. Respiratory vasculitis and classical PAN are significantly different, that is, respiratory vasculitis are not necessarily all have granulomas, nor the symptoms of PAN. PAN vasculitis lesions found in the muscular artery to the middle muscular artery; Li respiratory system vasculitis is the fine arteries and veins have changed. Pathologically, respiratory vasculitis is divided into Wegener’s granulomatous (WG), Churg-Strauss syndrome (C-S) and pleomorphic reticular cell disease (PMR) / lymphomagetic granulomagioma (LG) It is beneficial to the clinician to identify, diagnose and accurately estimate the prognosis and determine the treatment method.