目的:观察国产司帕沙星注射液治疗急性细菌性感染的疗效和不良反应。方法:共治疗病人60例,随机分为试验、对照及开放组各20例。结果:试验及开放组共40例,总有效率和细菌清除率为95％和93.5％;对照组20例,总有效率和细菌清除率为80％和88.9％。用药中不良反应较轻,试验及开放组发生率5％,对照组发生率10％。结论:提示本药治疗临床常见的中重度急性细菌性感染疗效高,毒副作用小。 Objective: To observe the efficacy and side effects of domestic sparfloxacin injection in the treatment of acute bacterial infections. Methods: A total of 60 patients were treated, randomly divided into experimental, control and open group of 20 cases. Results: Totally 40 cases were tested and open group. The total effective rate and bacterial clearance rate were 95% and 93.5%. In the control group, the total effective rate and bacterial clearance rate were 80% and 88.9% respectively. Adverse reactions in the treatment of lighter, test and open group incidence of 5%, the control group incidence of 10%. Conclusion: This medicine suggests that the treatment of common moderate-severe acute bacterial infections in clinical medicine has high curative effect and small toxic and side effects.