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麦迪霉素是一种适应症很广、安全可靠、问世较晚的大环内酯类抗生素。麦迪霉素属于快速抑菌剂。其作用机理是,当麦迪霉素进入菌体后,通过有效成份与细胞质内核糖体的50S亚基相结合,抑制移位酶,妨碍肽链合成过程中的移位反应,故能阻断蛋白质肽链的延长,使细菌的蛋白质合成受到阻碍,同时可使细菌的细胞壁增厚,抑制细菌的生长繁殖,从而发挥其抗菌作用。麦迪霉素对化脓性球菌和肺炎支原体具有较强的活性,其中抗肺炎支原体的作用最强,其次按顺序分别为抗肺炎球菌、溶血
Midecamycin is a macrolide antibiotic with a wide range of indications, safe and reliable, and later come out. Midecamycin is a fast bacteriostatic agent. Its mechanism of action is that when midecamycin enters the cell, it binds to the 50S subunit of ribosome in the cytoplasm to inhibit the translocase and impede the translocation reaction in the process of peptide synthesis, thus blocking the protein Stretching of the peptide chain hinders the bacterial protein synthesis, and at the same time, it can thicken the bacterial cell wall and inhibit the growth and reproduction of bacteria, thereby exerting its antibacterial effect. Midecamycin on pyogenic cocci and Mycoplasma pneumoniae has a strong activity, of which the strongest role of anti-Mycoplasma pneumoniae, followed by the order of anti-pneumococcus, hemolysis