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[目的]比较适形与调强基础上合成叠加调强计划的剂量学差异。[方法]选取根治性放疗直肠癌靶区,第一程计划分别用3野适形、4野适形和5野调强对PTV给予50Gy,在第一程计划基础上合成调强计划(IMRT)给予PGTV到66Gy根治剂量。危及器官都不超量的情况下比较靶区等效生物剂量。[结果]3个叠加后计划无明显差异。不考虑第一程计划,第二程计划差异明显,PGTV 95%剂量:5野剂量为15Gy,4野剂量为13.18Gy,3野剂量为8.82Gy。[结论]直肠癌根治性放疗局部加量调强基础上的合成计划等效生物剂量更接近预期值。
[Objective] To compare the dosimetry differences of the combined superposition intensification program based on conformal and intensity-modulated. [Method] The target of radical radiotherapy for rectal cancer was selected. PTG was given 50Gy in the first pass with 3F conformality, 4F conformality and 5F intensity respectively. On the basis of the first plan, IMRT ) Was given PGTV to a 66 Gy radical dose. Target organs equivalent biological dosages are compared in the absence of excessive organs. [Results] There was no significant difference between the three superposition plans. Without regard to the first-pass program, the second-step program differed significantly with 95% of PGTV doses: 15Gy for 5 doses, 13.18Gy for 4 doses and 8.82Gy for 3 doses. [Conclusion] The equivalent bio-dose of the synthetic scheme based on the local dose-escalation of radical radiotherapy for rectal cancer is closer to the expected value.