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目的探究神经节苷脂早期应用于急性脑梗死对神经功能恢复的影响。方法 50例急性脑梗死患者,随机分成治疗组和对照组,各25例。对照组常规应用活血化瘀、抗血小板聚集、促进脑细胞代谢、调控血压、血糖、血脂等药物治疗;治疗组在以上常规治疗的同时,(在发病24 h内)联用神经节苷脂治疗,60 mg/d,两组均治疗2周,观察两组疗效。结果治疗14 d后两组患者神经功能缺失评分(CNFDS)比治疗前都有所降低,但治疗组降低更明显,差异有统计学意义(P<0.01)。结论神经节苷脂早期应用对神经功能有保护作用,值得推广。
Objective To explore the effect of ganglioside applied to the recovery of nerve function in acute cerebral infarction. Methods Fifty patients with acute cerebral infarction were randomly divided into treatment group and control group, with 25 cases in each. The control group routinely applied blood-activating and blood-stasis, anti-platelet aggregation, promoting the metabolism of brain cells, regulating blood pressure, blood sugar, blood lipids and other drugs. In the treatment group, the above routine treatment was combined with ganglioside treatment , 60 mg / d, two groups were treated for 2 weeks, the two groups were observed. Results After 14 days of treatment, the neurological deficit scores (CNFDS) of both groups were lower than those before treatment, but the treatment group decreased more obviously with significant difference (P <0.01). Conclusion Early application of gangliosides has neuroprotective effects and is worth promoting.