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为扩大Norplant~R皮下埋植剂生育调节法的应用范围,对这种使用5年的长效仅含孕激素的埋植剂进行了避孕效果和可接受性及可逆性的评价。1985年5月～11月,根据人口理事会避孕研究国际委员会制订的标准(年龄18～40岁,至少有过一次生育,有性活动,埋植时非妊娠及非哺乳,无应用甾体激素的禁忌症,研究期内不应用其它避孕措施)筛选出100例受试者。放置前充分向受试者说明研究目的、使用此法的利与弊,并取得受试者同意。埋植后1、3、6、12个月及以后每年2次随访和出现问题时的计划外随访。结果:受试者平均年龄29.5岁,产次(分娩活婴)2.1,平均受教育7.8年。5年
In order to expand the application of fertility regulation method of Norplant ~ R subcutaneous implants, the contraceptive effect and acceptability and reversibility of this 5-year long-term progestogen-only implants were evaluated. From May to November 1985, according to the criteria established by the International Council on Contraceptive Research of the Population Council (aged 18-40 years, there was at least one childbirth, sexual activity, non-pregnancy and non-breastfeeding at implantation, no application of steroid hormone Of contraindications, during the study period should not use other contraceptive measures) screening of 100 subjects. Before placement, fully explain the research purpose to the subjects, use the pros and cons of this method, and obtain the consent of the subjects. Unplanned follow-up at 1, 3, 6, 12 months after implantation and 2 years after follow-up when problems arose. Results: The average age of subjects was 29.5 years old, parity (delivery of live births) 2.1, average education 7.8 years. 5 years