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目的评价聚焦超声在农村基层医院治疗宫颈炎症相关疾病的有效性、安全性和适用性。方法在重庆市9区县80家乡镇医院进行多中心临床研究,采用CZF型超声波治疗仪,对8 352例宫颈炎症相关疾病患者行聚焦超声单次治疗后随访3个月,根据4级计分法和疗效指数评价方法,分析和评价有完整记录的7 027例患者(轻度1 156例、中度5 312例、重度559例)的治疗效果、安全性和适用性,采用非条件logistic回归分析探讨疗效的影响因素。结果 7 027名患者中6 413例(91.26%)在5分钟内完成聚焦超声治疗。经3个月随访观察,总有效率为99.59%,5 012例(71.32%)治愈。656例(9.34%)治疗后有少-中量阴道出血,仅12例患者(占0.17%)的出血量与月经量相当,经压迫止血及对症抗炎治疗后血止。结论聚焦超声是治疗宫颈炎症相关疾病安全有效的新疗法,术后出血少,阴道排液时间短,适合在基层农村地区推广使用。
Objective To evaluate the effectiveness, safety and applicability of focused ultrasound in the treatment of cervical inflammation related diseases in rural primary hospitals. Methods A multicenter clinical study was conducted in 80 township hospitals in 9 districts and counties of Chongqing. CZF ultrasonic therapeutic apparatus was used to evaluate 8 352 cases of cervical inflammation-related diseases followed up for 3 months after single-stage ultrasound treatment. According to grade 4 Method and efficacy index evaluation method, the treatment effect, safety and applicability of 7 027 patients (mild 1,156 mild, moderate 5,312, severe 559) with complete records were analyzed and evaluated. Non-conditional logistic regression Analyze and discuss the influencing factors of curative effect. Results 6 413 (91.26%) of 7 027 patients completed focused ultrasound within 5 minutes. After 3 months of follow-up, the total effective rate was 99.59% and 5 012 cases (71.32%) were cured. After treatment, 656 patients (9.34%) had less - moderate vaginal bleeding, and only 12 patients (0.17%) had similar amount of bleeding and menstrual flow. After compression hemostasis and symptomatic anti - inflammatory treatment, blood was collected. Conclusions Focused ultrasound is a safe and effective new treatment for cervical inflammation-related diseases. It has less postoperative bleeding and shorter vaginal discharge time. It is suitable for promotion and use in primary rural areas.