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目的探讨早期干预对新生儿缺氧缺血性脑病(HIE)预后的作用效果。方法HIE患儿随机分为干预组和对照组,干预组给予早期干预,包括神经细胞康复治疗和功能康复治疗,于生后3、6、12个月对两组患儿进行体格和精神运动两方面的检查评价。结果两组患儿3、6、12个月龄时身高、体质量、头围之间的比较差异均无统计学意义,干预组3、6、12个月龄发育商(DQ)分别为91.45±8.62、89.08±8.25、88.16±8.06,与对照组比较,差异有统计学意义。结论早期干预可促进HIE患儿的精神运动发育,减少后遗症,改善其预后。
Objective To investigate the effect of early intervention on the prognosis of neonatal hypoxic-ischemic encephalopathy (HIE). Methods HIE children were randomly divided into intervention group and control group. The intervention group was given early intervention, including nerve cell rehabilitation and functional rehabilitation. Two groups of children were subjected to physical and mental exercise at 3, 6 and 12 months after birth Aspects of the inspection and evaluation. Results There was no significant difference in height, body weight and head circumference between the two groups at 3, 6 and 12 months of age. The DQ of 3, 6, and 12 months of intervention group were 91.45 ± 8.62,89.08 ± 8.25,88.16 ± 8.06, the difference was statistically significant compared with the control group. Conclusion Early intervention can promote the development of psychomotor in children with HIE, reduce sequelae and improve their prognosis.