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目的观察分析通脉养心丸联合美托洛尔治疗冠心病心绞痛的临床疗效。方法选择医院收治的106例冠心病心绞痛患者为研究对象,随机分为观察组和对照组,每组53例。对照组在常规治疗基础上给予美托洛尔治疗,观察组在对照组治疗的基础上给予通脉养心丸治疗。治疗后,比较2组患者的临床疗效、心电图改善情况及不良反应发生率。结果观察组临床治疗总有效率为88.7%,高于对照组的71.7%(P<0.05);观察组心电图改善总有效率为92.5%,明显高于对照组的69.8%(P<0.01)。2组患者高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、总胆固醇、C-反应蛋白、三酰甘油等生化指标比较,差异均无统计学意义(P>0.05);2组患者均未出现明显的不良反应。结论冠心病心绞痛患者采取通脉养心丸联合美托洛尔治疗,效果显著,安全性高,值得在临床推广应用。
Objective To observe the clinical effect of Tongmai Yangxin Pills combined with metoprolol in the treatment of coronary heart disease angina pectoris. Methods A total of 106 patients with coronary heart disease and angina pectoris admitted to the hospital were selected as study subjects and randomly divided into observation group and control group with 53 cases in each group. The control group was treated with metoprolol on the basis of routine treatment, and the observation group was given Tongmai Yangxin Wan on the basis of the control group. After treatment, the clinical efficacy, the improvement of electrocardiogram and the incidence of adverse reactions in two groups were compared. Results The total effective rate of observation group was 88.7%, higher than 71.7% of control group (P <0.05). The total effective rate of observation group was 92.5%, significantly higher than that of control group (69.8%, P <0.01). There were no significant differences in biochemical indexes of HDL-C, LDL-C, total cholesterol, C-reactive protein and triglyceride between the two groups (P> 0.05) Adverse reactions. Conclusions Coronary heart disease patients with angina pectoris Tongmai Yangxin pills combined with metoprolol treatment, the effect is significant, safe, it is worth in the clinical application.