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目的：探讨糖尿病自主神经病变与糖尿病肾病之间的关系。方法：将４６例非胰岛素依赖型糖尿病（ＮＩＤＤＭ）患者按有无自主神经病分成两组，分别测定尿白蛋白排泄率（ＵＡＥＲ）。结果：伴自主神经病变组（ＡＮ组）夜间ＵＡＥＲ明显高于无自主神经病变组（无ＡＮ组），且与卧立位血压差和自主神经计分呈显著正相关。结论：自主神经病变使ＮＩＤＤＭ患者夜间ＵＡＥＲ增加，促进糖尿病肾病的发展。
Objective: To investigate the relationship between diabetic autonomic neuropathy and diabetic nephropathy. Methods: 46 patients with non-insulin dependent diabetes mellitus (NIDDM) were divided into two groups according to the presence or absence of autonomic neuropathy. Urinary albumin excretion rate (UAER) was measured. Results: The nighttime UAER in patients with autonomic neuropathy (AN group) was significantly higher than that in patients without autonomic neuropathy (without AN group), and was positively correlated with lying pressure and autonomic nerve score. Conclusion: Autonomic neuropathy increases Nocturnal UAER in patients with NIDDM and promotes the development of diabetic nephropathy.