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目的观察生大黄联合乌司他汀治疗重症急性胰腺炎的临床疗效。方法入选济宁市附属医院住院确诊的重症急性胰腺炎患者88例,随机分成治疗组、对照组两组。对照组给予禁饮食、胃肠减压、抑酸、抗生素、补充血容等对症支持治疗,治疗组在上述治疗基础上加用生大黄粉及乌司他汀。结果生大黄联合乌司他汀治疗后,治疗组CRP浓度、血尿淀粉酶、白细胞数均较对照组显著降低,肝功能损害较入院时明显好转。结论生大黄联合乌司他汀治疗重症急性胰腺炎疗效好。
Objective To observe the clinical efficacy of rhubarb combined with ulinastatin in the treatment of severe acute pancreatitis. Methods Totally 88 patients with severe acute pancreatitis admitted to Jining Affiliated Hospital were randomly divided into treatment group and control group. Control group was given banned diet, gastrointestinal decompression, acid suppression, antibiotics, blood and other symptomatic supportive treatment, the treatment group based on the above treatment plus raw rhubarb powder and ulinastatin. Results Raw rhubarb combined with ulinastatin treatment, CRP concentration in the treatment group, hematuria, amylase, white blood cell count were significantly lower than the control group, liver dysfunction than hospital admission was significantly improved. Conclusions Raw rhubarb combined with ulinastatin in the treatment of severe acute pancreatitis has good curative effect.