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人类免疫缺陷病毒(HIV)感染后,较常见表现有淋巴结病、发热、体重减轻和血小板减少,约30%在3-5年后出现AIDS。HIV伴发的血小板减少与典型的免疫性血小板减少性紫癜(ITP)十分相似,目前的治疗方法有类固醇激素和脾切除术。作者总结了脾切除治疗的经验。方法和结果:1984年1月-1987年8月31日共治疗11例,都是Western印迹试验阳性或Th/Ts倒置的HIV感染者,全部为男性同性恋者,平均年龄32.6岁。7例血清检查证实有乙型肝炎。以往无提示AIDS的条件致病菌感染或肿瘤;均有青紫和/或齿龈出血,1例反复出现自发性鼻衄,无致命性出血。所有病例从初诊至脾切平均观察6.45个月(2-18个月)
After the human immunodeficiency virus (HIV) infection, the more common manifestations are lymphadenopathy, fever, weight loss and thrombocytopenia, and about 30% develop AIDS after 3-5 years. HIV-associated thrombocytopenia is very similar to the classic immune thrombocytopenic purpura (ITP), and current treatments include steroid and splenectomy. The authors summarize the experience of splenectomy treatment. Methods and Results: From January 1984 to August 31, 1987, a total of 11 patients were treated, all of whom were HIV-positive with Western blotting test or with Th / Ts inversion. All of them were gay men with a mean age of 32.6 years. Seven cases of hepatitis B confirmed serum tests. In the past, there was no pathogenic infection of AIDS or tumor; all had purple and / or gingiva bleeding, 1 case of recurrent spontaneous epistaxis, non-fatal bleeding. All cases from the initial diagnosis to the spleen were observed for an average of 6.45 months (2-18 months)