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目的探讨难以确诊鼻腔恶性淋巴瘤的临床特点、误诊原因、诊断方法。方法回顾性分析2006年至2015年7例难以确诊的鼻腔恶性淋巴瘤临床病理资料。分析患者发病年龄、首发症状、阳性体征及确诊前病程。结果难以确诊鼻腔恶性淋巴瘤患者好发于中老年,男性多见;首发临床症状多无特异性;确诊前病程为2~5年。结论难以确诊鼻腔恶性淋巴瘤首发症状多无特异性,有较高的误诊率。确诊须依靠病理检查及免疫组化。
Objective To investigate the clinical features, misdiagnosis and diagnosis of nasal malignant lymphoma. Methods Retrospective analysis of 7 cases of difficult to diagnose nasal malignant lymphoma from 2006 to 2015 clinical and pathological data. Analysis of patient age, first symptom onset, positive signs and pre-diagnosis course. The results are difficult to diagnose patients with nasal malignant lymphoma occur in middle-aged and elderly, more common in men; first clinical symptoms more non-specific; diagnosis of course of 2 to 5 years. Conclusion The first symptom of nasal malignant lymphoma, which is difficult to diagnose, is more non-specific and has a higher misdiagnosis rate. Diagnosis depends on pathological examination and immunohistochemistry.