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我们观察12例连续应用地高辛的风心瓣膜病合并房颤(Af)患者,在心电图28例次提示二度房室传导阻滞(Ⅱ°A—VB)时测定血浆地高辛浓度(PDC),以探讨Af并Ⅱ°A—VB与地高辛中毒的关系。观察对象,均为本院住院风心Af患者共12例,男女各6例,年龄33～60岁,共统计28例次口服地高辛过程中心电图Ⅱ°A—VB时的PDC。检查方法和诊断标准: 1.PDC测定方法:采用血清肌酐法,正常值0.8～2.0毫微克/毫升(ng/ml)。
We observed 12 consecutive patients with rheumatic valvular heart disease complicated with atrial fibrillation (Af) treated with digoxin, and measured plasma concentrations of digoxin (Ⅱ A-VB) at 28 ECG secondary prompts of second degree atrioventricular block PDC) to explore the relationship between Af and Ⅱ ° A-VB and digoxin poisoning. Observed objects were all 12 patients with Af who were hospitalized with rheumatoid arthritis in our hospital. There were 6 males and 6 females aged from 33 to 60 years old. A total of 28 PDC patients underwent oral digoxin treatment with Ⅱ ° A-VB electrocardiogram. Inspection methods and diagnostic criteria: 1. PDC determination: serum creatinine method, the normal value of 0.8 to 2.0 ng / ml (ng / ml).