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目的了解我院药品不良反应(ADR)发生的特点及一般规律,以及给患者带来的危害。为临床合理安全用药提供参考。方法对322例ADR病例报告进行分类统计和分析评价。结果引起ADR的药物共有125个品种,其中抗菌药物居首位,其次为中草药制剂、循环系统药物。合并用药占52.17%;途径以静脉用药为主。主要的ADR类型为皮肤及其附件损害,消化系统损害、其次是全身性损害。严重的ADR7例(2.17%)。结论应充分认识到ADR监测的重要性,要加强ADR的监测工作,以减少ADR的重复发生。
Objective To understand the characteristics and general rules of adverse drug reaction (ADR) in our hospital and the harm to patients. Provide a reference for clinical rational and safe medication. Methods The data of 322 cases of ADR were classified and analyzed. Results There were 125 varieties of drugs that caused ADR, among which antibacterials ranked first, followed by Chinese herbal preparations and circulatory system drugs. Consolidation medication accounted for 52.17%; route to intravenous drug-based. The main types of ADR damage the skin and its accessories, digestive system damage, followed by systemic damage. Severe cases of ADR (2.17%). Conclusion The importance of ADR monitoring should be fully recognized. Monitoring of ADR should be strengthened to reduce the recurrence of ADR.