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目的:了解烧伤患者血清肌钙蛋白I(cTnI)在伤后不同阶段的变化情况。方法:分别测定60例烧伤患者在急性期、修复期、并发症期血清中cTnI,同时检测谷氨酰转移酶(AST)、肌酸激酶(CK)、肌酸激酶同功酶(CK-MB)、乳酸脱氢酶(LDH)、α-羟丁酸脱氢酶(α-HBDH)。对部分患者进行心电图动态监测。结果:急性期,部分患者cTnI有不同程度升高。修复期,有面部烧伤和呼吸道症状的患者,其cTnI升高率达65%,且异常增高。并发症期,如有创面感染和全身炎症反应综合征的其cTnI仍持续升高。结论:cTnI是体现烧伤患者心肌损伤的特异性指标之一。
Objective: To understand the changes of cTnI in burn patients at different stages after injury. Methods: The levels of cTnI in serum of 60 cases of burn patients during acute phase, repair phase and complication phase were measured respectively. The levels of AST, CK, CK-MB ), Lactate dehydrogenase (LDH), alpha-hydroxybutyrate dehydrogenase (alpha-HBDH). Some patients on the ECG dynamic monitoring. Results: Acute phase, some patients cTnI increased to varying degrees. In the reparative phase, patients with facial burns and respiratory symptoms had an elevated cTnI of 65% with an abnormal increase. Complications, such as wound infection and systemic inflammatory response syndrome cTnI continued to rise. Conclusion: cTnI is one of the specific indicators of myocardial injury in patients with burn.