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目的:探讨在结肠镜检查治疗前肠道准备中使用硫酸镁联合口服补液盐清肠方法的应用。方法:对125例服用硫酸镁联合口服补液盐(研究组)与125例服用甘露醇联合5%葡萄糖氯化钠溶液(对照组)结肠镜检查治疗前行肠道准备的患者进行随机、对照临床研究,以肠道准备质量、患者舒适度为主要疗效评价指标,并记录严重不良事件。结果:研究组与对照组在肠道清洁程度、患者清肠过程的舒适度方面差异无统计学意义,但对照组共有6例结肠癌并狭窄患者,其中3例出现肠梗阻,而研究组中共有7例结肠癌患者均未发生肠梗阻。结论:硫酸镁联合口服补液盐清肠是一种快捷、高效、安全、经济、患者耐受性好的清肠方法。
Objective: To explore the application of magnesium sulfate combined with oral rehydration salt bowel preparation in intestinal preparation before colonoscopy. METHODS: A total of 125 patients undergoing colonoscopy with magnesium sulfate in combination with oral rehydration salts (study group) and 125 mannitol plus 5% glucose sodium chloride solution (control group) colonoscopy were enrolled in a randomized, controlled clinical Study, to gut preparation quality, patient comfort as the main evaluation index, and record serious adverse events. Results: There was no significant difference between the study group and the control group in the degree of intestinal tract cleanliness and the comfort of patients during bowel clearance. However, there were 6 cases of colon cancer and stenosis in the control group, including 3 cases of intestinal obstruction. In the study group A total of seven cases of colon cancer patients did not occur intestinal obstruction. Conclusion: Magnesium sulfate combined with oral rehydration salt bowel is a fast, efficient, safe, economical, well-tolerated bowel method.