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目的观察养正祛瘀方联合米非司酮治疗子宫肌瘤的临床效果。方法将69例子宫肌瘤患者随机分为研究组34例和对照组35例。研究组采用养正祛瘀方联合非司酮治疗,对照组仅服用米非司酮治疗。月经期停服,连服3个月后对比观察2组子宫、子宫肌瘤体积大小、孕酮水平的改变。结果研究组总有效率为94.12%高于对照组的74.29%,差异有统计学意义(P<0.05)。治疗前2组子宫体积、子宫肌瘤体积和孕酮水平比较差异无统计学意义(P>0.05)。治疗后,2组患者子宫体积和子宫肌瘤体积均减小,孕酮水平均降低,且研究组降低幅度大于对照组,差异均有统计学意义(P<0.05)。结论养正祛瘀方联合西药米非司酮治疗子宫肌瘤临床疗效显著,可有效降低血清中孕酮含量,缩小子宫和子宫肌瘤的体积,对临床治疗子宫肌瘤具有重要意义。
Objective To observe the clinical effects of Yangzhengquyu recipe combined with mifepristone in treating uterine fibroids. Methods 69 patients with uterine fibroids were randomly divided into study group 34 cases and control group 35 cases. The study group was treated with Yangzheng Quyu Decoction and the control group only with mifepristone. Menstrual period stopped taking clothes, and even after 3 months of service compared to observe the 2 groups of uterine fibroids size, the level of progesterone changes. Results The total effective rate of the study group was 94.12% higher than that of the control group (74.29%), the difference was statistically significant (P <0.05). There was no significant difference in uterine volume, uterine leiomyoma volume and progesterone level between the two groups before treatment (P> 0.05). After treatment, the volume of uterine fibroids and the volume of uterine fibroids in both groups decreased and the progesterone levels decreased. The reduction rate in the study group was greater than that in the control group (P <0.05). Conclusion Yang Zheng Qu Yu Fang combined with western medicine mifepristone treatment of uterine fibroids clinically significant effect, can effectively reduce the serum progesterone content, reduce the size of uterine and uterine fibroids, the clinical treatment of uterine fibroids is of great significance.