目的研究艾司唑仑对老年失眠患者吞咽功能的影响。方法将82例老年失眠患者按随机数字表法分为观察组(42例)和对照组(40例)。观察组每晚给予艾司唑仑1 mg,对照组则予安慰剂。在治疗前和治疗4周后分别对入组患者进行洼田饮水试验、进食评估问卷调查工具-10(EAT-10)量表和视频透视吞咽检查(VFSS)。结果治疗前后比较,观察组的洼田饮水试验评级和EAT-10量表评分均有显著提高,VFSS评分显著下降,差异均具有统计学意义(均P<0.05)。与对照组治疗4周后比较,观察组患者的洼田饮水试验评级和EAT-10量表评分也有显著升高,VFSS评分显著降低,组间差异均具有统计学意义(Ρ<0.05)。结论艾司唑仑可以加重老年失眠患者的吞咽障碍。 Objective To study the effect of estazolam on swallowing function in elderly patients with insomnia. Methods 82 elderly patients with insomnia were randomly divided into observation group (42 cases) and control group (40 cases). The observation group received estazolam 1 mg every night, while the control group received placebo. Before treatment and after 4 weeks of treatment, the patients in each group were subjected to the Kudzu Water Test, the Food Assessment Questionnaire-10 (EAT-10) Scale, and the Video Vital Swallowing Examination (VFSS). Results Before and after treatment, the Kubota drinking water test rating and EAT-10 scale scores of the observation group were significantly increased, while the VFSS scores were significantly decreased (all P <0.05). Compared with the control group after 4 weeks of treatment, the Kubota drinking water test rating and the EAT-10 scale score in the observation group were significantly increased, and the VFSS score was significantly decreased. The differences between the two groups were statistically significant (P <0.05). Conclusion Estazolam can aggravate dysphagia in elderly patients with insomnia.