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目的探讨中西医结合治疗慢性乙型肝炎的疗效及临床分析。方法 2007年9月至2011年9月期间,我院诊治的171例慢性乙型肝炎患者,随机将其分为对照组(单纯西药治疗)和观察组(中西医结合治疗),治疗12个月后,对两组肝功能、HBV血清标志物转阴率,以及血清肝纤维化指标,进行观察和比较。结果与对照组相比,治疗后观察组谷丙转氨酶ALT、谷草转氨酶AST、总胆红素TBIL水平明显降低,HBeAg和HBV-DNA转阴率明显升高,透明质酸HA、层粘连蛋白LN、Ⅲ型前胶原PCIII、IV型胶原IV-C水平显著降低,P<0.05,差异有统计学意义。结论中西医结合治疗慢性乙型肝炎疗效显著,显著改善患者预后质量,值得临床推广。
Objective To investigate the curative effect and clinical analysis of treating chronic hepatitis B with integrated traditional Chinese and western medicine. Methods From September 2007 to September 2011, 171 chronic hepatitis B patients treated in our hospital were randomly divided into control group (Western medicine only) and observation group (Integrative medicine) for 12 months After the two groups of liver function, HBV seroconversion rate, and serum liver fibrosis indicators were observed and compared. Results Compared with the control group, the levels of ALT, AST and TBIL in the observation group decreased significantly after treatment, and the negative rates of HBeAg and HBV-DNA were significantly increased. The levels of HA, laminin LN , Type III procollagen PCIII, type IV collagen IV-C levels were significantly lower, P <0.05, the difference was statistically significant. Conclusion The treatment of chronic hepatitis B with traditional Chinese and western medicine has significant curative effect, significantly improves the quality of prognosis of patients and deserves clinical promotion.