我院近4年接诊应用人胰岛素治疗患者1560例,发现有6例人胰岛素过敏并经脱敏治疗病例,现报告如下。1女性,73岁,2型糖尿病史20年,有青霉素过敏史,在门诊注射重组人胰岛素诺和灵30R早14u,晚10u2周后,出现耳廓水肿,颈部水泡。停用胰岛素,1个月后恢复正常,血糖升至空腹14mmol/L,改用 Nearly 4 years in our hospital admissions application of insulin treatment of 1560 patients, found that 6 cases of human insulin allergy and desensitization treatment cases are as follows. A female, 73 years old, type 2 diabetes history of 20 years, history of penicillin allergy, intravenous injection of recombinant human insulin Novolin 30R early 14u, 10u2 weeks later, auricle edema, neck blisters. Disable insulin, returned to normal after 1 month, blood sugar rose to fasting 14mmol / L, switch to use