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特应性皮炎是一种反复发作的炎症性皮肤病，现有的治疗方法虽能缓解症状，但仍存在一定的局限性及不良反应。近年来，随着特应性皮炎关键炎症分子的发现和靶向治疗药物的开发，给临床带来一些新的治疗方法和理念。了解特应性皮炎相关生物制剂、小分子药物、辅助治疗、监测手段和疾病管理模式新进展，有助于临床医生更好地治疗及管理特应性皮炎患者。“,”Atopic dermatitis is a recurrent inflammatory skin disease. Although the existing systemic and topical treatment can relieve symptoms, there are still some limitations and adverse effects. In recent years, with the in-depth study on the pathogenesis of atopic dermatitis, especially the discovery of key inflammatory molecules and development of targeted therapeutic drugs, some new therapeutic methods and concepts have been brought to clinical practice. Awareness of new progress in atopic dermatitis-related biologics, small-molecule drugs, adjuvant treatment, monitoring methods and models for managing disease, will help clinicians better treat and manage atopic dermatitis.