【摘 要】
：
胃食管反流病(GERD)十分常见.作为一种以反流、烧心为主诉的功能性疾病,GERD的病理生理和发病机制非常复杂和微妙.长期胃内容物和胆汁反流不仅可以引起黏膜炎性改变,而且可以
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胃食管反流病(GERD)十分常见.作为一种以反流、烧心为主诉的功能性疾病,GERD的病理生理和发病机制非常复杂和微妙.长期胃内容物和胆汁反流不仅可以引起黏膜炎性改变,而且可以诱发鳞状上皮的柱状化生、不典型增生和食管癌.因此,控制症状、治疗并发症并对肿瘤高危患者做出有效随访和干预,是治疗GERD的3个重要组成部分.口服质子泵抑制剂( PPI)和改变生活习惯可以治疗绝大部分GERD.外科抗反流手术指征包括PPI药物治疗无效、合并并发症和食管裂孔疝的患者.腹腔镜微创抗反流技术的推出,极大地提高了抗反流手术的接受度,但远期并发症并未减少.因此,如Linx磁力环在内的更多新的外科手段急待推出.
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