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自1960年起,血清肌酸激酶(CK)活性作为肌肉损伤的敏感指示剂已广泛应用,随后认识到CK异构酶(MM,MB和BB)可增加诊断的特异性。
Since 1960, serum creatine kinase (CK) activity has been widely used as a sensitive indicator of muscle damage, and it was subsequently recognized that CK isomerases (MM, MB, and BB) increase the diagnostic specificity.