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血小板源生长因子 (PDGF)是机体内主要的促分裂剂和趋化剂之一 ,PDGF是一个二聚体家族 ,至少由四种不同的基因表达产物组成。最近 ,PDGF B链的基因转录调控日益受到重视 ,一些顺式调控元件和相应的反式作用因子已被证实。
Platelet-derived growth factor (PDGF) is one of the major mitogen and chemotactic agents in the body. PDGF is a dimeric family consisting of at least four distinct gene expression products. Recently, the transcriptional regulation of the PDGF B chain is gaining more and more attention. Some cis-regulatory elements and corresponding trans-acting factors have been confirmed.