利用锑制剂治疗黑热病,始于1913年,当时系用三价锑化合物——酒石酸锑钾;至1916年又增用五价有机锑化合物,称为斯锑保雪汀(Stibacetin),二者的毒性都高,死亡率均在95%以上。至1922年以后,直至解放前,在我国市场上,即先后从国外输入尿素斯锑保命(Urea Stibamine)、新斯锑波霜(Neo-Stibosan)、圣露斯锑波霜(Solustibosan),和本妥斯登(Pentostam)等五价锑制剂治疗黑热病,但均价格昂贵,病人无法负担,以致不治身死,仍 The use of antimony preparations for the treatment of kala-azar, began in 1913, when the system was a trivalent antimony compound - antimony potassium tartrate; to 1916 and the use of pentavalent organic antimony compounds, known as stibine Stibacetin (Stibacetin), both Toxicity is high, mortality rates were above 95%. Until 1922, Urea Stibamine, Neo-Stibosan, Solustibosan, and so on were imported into our country from the beginning of the liberation until the liberation. Pentostam and other pentavalent antimony preparations for the treatment of kala-azar, but are expensive, the patient can not afford to be dead, still