近年文献屡有报告重症沙门氏菌属感染能够引起脑水肿、肺水肿及急性肾功能衰竭,并常导致死亡。而于上述并发症的同时,往往并发有休克。本病所致休克发病原理也是多方面的,多属于感染—中毒性休克(细菌性或内毒素性休克)、低血容量性休克与混合性休克。当休克时可发生急性血液动力学与微循环障碍以及代谢的变化。微循环障碍分全身性或系统性与局部性(如脑、肺、肾等)。引起这些变化的原因有:细菌及其毒素的中毒 In recent years, the literature has repeatedly reported severe Salmonella infection can cause cerebral edema, pulmonary edema and acute renal failure, and often lead to death. In the above complications at the same time, often complicated by shock. The pathogenesis of shock caused by the disease is also multifaceted, mostly belonging to infection - toxic shock (bacterial or endotoxic shock), hypovolemic shock and mixed shock. Acute hemodynamic and microcirculatory disturbances and metabolic changes can occur when shocked. Microcirculation disorders were sub-systemic or systemic and local (such as brain, lung, kidney, etc.). Reasons for these changes are: poisoning of bacteria and their toxins